The Justice Ministry said in a statement that Mrs Netanyahu stands accused of misusing public funds by fraudulently ordering hundreds of meals to the prime minister’s official residence worth over $100,000 while falsely stating there were no cooks on the staff.
A former deputy dericter of the prime ministeer’s residence is also charged in the case.
suspected of receiving $285,000 worth of luxury cigars, champagne and jewellery from wealthy personalities in exchange for financial or personal favour.
In the other case, investigators suspect the premier of trying to reach an agreement with the owner of Yediot Aharonot, a top Israeli newspaper, for more favourable coverage.
Mr Netanyahu has denied any wrong doing, dismissing the accusations against him and his wife as a media witch hunt.
He also faces suspicions of government favours that allegadly saw regulatory breaks go to Israel’s Iargest telecom firm Bezeq, in return for favourable coverage of him and his wife by a news website.
Despite his troubles, opinion polls suggest Mr Netanyahu’s right-wing likud party would remain the largest in parliament if elections scheduled for November 2019 were held now.